Science

Mixing Pfizer and Moderna shows better outcome, UK study says

09:50, 08 December 2021
Mixing Pfizer and Moderna shows better outcome, UK study says Photo: pixabay.com

British researchers have found out that mixing vaccines against coronavirus can trigger a better immunity response, so the jab of Pfizer-BioNTech or AstraZeneca followed by Moderna after nine weeks is more effective than two doses of the same vaccine.


The study was carried out by researchers at Oxford University and based on reactions of the immune system of 1,070 volunteers who mixed Pfizer, AstraZeneca, Novavax, and Moderna jabs.

Thus the individuals who were first inoculated with AstraZeneca and later got either Moderna or Novavax jab have produced a greater number of antibodies and T-cell responses compared to the people who were injected with two doses of AstraZeneca.

The research has also revealed that a Pfizer jab followed by Novavax showed better results than two doses of AstraZeneca, but the immune system response is lower than after two doses of Pfizer.

“We’re showing… you don’t have to stick rigidly to receiving the same vaccine for a second dose… and that if the programme will be delivered more quickly by using multiple vaccines, then it is okay to do so,” the Oxford professor of Com-COV2 study, Matthew Snape, told Reuters.

The results of the research give hope in increasing the situation with COVID-19 to poor or middle-income countries as they keep struggling from the lack of vaccines. It would allow people to receive the second dose of another vaccine if the country runs out of the supply of the first type they were inoculated with.

As of now, the vaccination rate among poor countries remains low showing that just 6,3% of people in low-income received at least one dose against coronavirus, according to Our World in Data organization.